It is reported that great ___made to look into the case have paid off.

a.attentionb.effortsc.troublesd.cares

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b.efforts努力句子可还原为：It is reported that great made to look into the case have paid off.其中 在that从句中作主语，made to look into the case做后置定语修饰，它可改为定语从句－－－...which were made to look into the case...换句话说 make 和efforts是搭配在一起的，构成词组make great efforts to do sth,其他几个选项都不和make搭配。句意：据报道，对该案件调查巨大努力已经有了结果。

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i think Zhaorentao2005's answer is the best, take it, you won't regret.

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B 正确 make great efforts 做出的努力据报道,调查这件事所做出的努力值得

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make great efforts to 花巨大的努力pay attention to

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A

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b.efforts努力据报道，经过巨大的努力，对该案的调查已经有了结果．因为调查需要的是努力，而不是Ａ的注意力，ＣＤ更离题．由于没有上下文，对case的翻译无从把握，呵呵．